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Next-Generation cDNA Screening for Oncogene and Resistance Phenotypes

There is a pressing need for methods to define the functional relevance of genetic alterations identified by next-generation sequencing of cancer specimens. We developed new approaches to efficiently construct full-length cDNA libraries from small amounts of total RNA, screen for transforming and re...

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Detalles Bibliográficos
Autores principales: Shindoh, Nobuaki, Yoda, Akinori, Yoda, Yuka, Sullivan, Timothy J., Weigert, Oliver, Lane, Andrew A., Kopp, Nadja, Bird, Liat, Rodig, Scott J., Fox, Edward A., Weinstock, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492311/
https://www.ncbi.nlm.nih.gov/pubmed/23145123
http://dx.doi.org/10.1371/journal.pone.0049201