Targeting COX-2/PGE(2) Pathway in HIPK2 Knockdown Cancer Cells: Impact on Dendritic Cell Maturation

BACKGROUND: Homeodomain-interacting protein kinase 2 (HIPK2) is a multifunctional protein that exploits its kinase activity to modulate key molecular pathways in cancer to restrain tumor growth and induce response to therapies. For instance, HIPK2 knockdown induces upregulation of oncogenic hypoxia-...

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Detalles Bibliográficos
Autores principales: Garufi, Alessia, Pistritto, Giuseppa, Ceci, Claudia, Di Renzo, Livia, Santarelli, Roberta, Faggioni, Alberto, Cirone, Mara, D’Orazi, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492329/
https://www.ncbi.nlm.nih.gov/pubmed/23144866
http://dx.doi.org/10.1371/journal.pone.0048342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492329/
https://www.ncbi.nlm.nih.gov/pubmed/23144866
http://dx.doi.org/10.1371/journal.pone.0048342

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