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c-Fms Signaling Mediates Neurofibromatosis Type-1 Osteoclast Gain-In-Functions
Skeletal abnormalities including osteoporosis and osteopenia occur frequently in both pediatric and adult neurofibromatosis type 1 (NF1) patients. NF1 (Nf1) haploinsufficient osteoclasts and osteoclast progenitors derived from both NF1 patients and Nf1(+/−) mice exhibit increased differentiation, mi...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492362/ https://www.ncbi.nlm.nih.gov/pubmed/23144792 http://dx.doi.org/10.1371/journal.pone.0046900 |