Paradoxical Impact of Two Folate Receptors, FRα and RFC, in Ovarian Cancer: Effect on Cell Proliferation, Invasion and Clinical Outcome

Despite being an essential vitamin, folate has been implicated to enhance tumor growth, as evidenced by reports on overexpression of folate receptor alpha (FRα) in carcinomas. The role of another folate transporter, reduced folate carrier (RFC), is largely unknown. This study investigated the roles...

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Detalles Bibliográficos
Autores principales: Siu, Michelle K. Y., Kong, Daniel S. H., Chan, Hoi Yan, Wong, Esther S. Y., Ip, Philip P. C., Jiang, LiLi, Ngan, Hextan Y. S., Le, Xiao-Feng, Cheung, Annie N. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492371/
https://www.ncbi.nlm.nih.gov/pubmed/23144806
http://dx.doi.org/10.1371/journal.pone.0047201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492371/
https://www.ncbi.nlm.nih.gov/pubmed/23144806
http://dx.doi.org/10.1371/journal.pone.0047201

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