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Hematopoietic Stem/Progenitor Cell Proliferation and Differentiation Is Differentially Regulated by High-Density and Low-Density Lipoproteins in Mice

RATIONALE: Hematopoietic stem/progenitor cells (HSPC) are responsible for maintaining the blood system as a result of their self-renewal and multilineage differentiation capacity. Recently, studies have suggested that HDL cholesterol may inhibit and impaired cholesterol efflux may increase HSPC prol...

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Detalles Bibliográficos
Autores principales: Feng, Yingmei, Schouteden, Sarah, Geenens, Rachel, Van Duppen, Vik, Herijgers, Paul, Holvoet, Paul, Van Veldhoven, Paul P., Verfaillie, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492382/
https://www.ncbi.nlm.nih.gov/pubmed/23144813
http://dx.doi.org/10.1371/journal.pone.0047286