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Identification of ATP-Binding Regions in the RyR1 Ca(2+) Release Channel
ATP is an important modulator of gating in type 1 ryanodine receptor (RyR1), also known as a Ca(2+) release channel in skeletal muscle cells. The activating effect of ATP on this channel is achieved by directly binding to one or more sites on the RyR1 protein. However, the number and location of the...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492408/ https://www.ncbi.nlm.nih.gov/pubmed/23144945 http://dx.doi.org/10.1371/journal.pone.0048725 |