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Effects of Growth and Mutation on Pattern Formation in Tissues

In many developing tissues, neighboring cells enter different developmental pathways, resulting in a fine-grained pattern of different cell states. The most common mechanism that generates such patterns is lateral inhibition, for example through Delta-Notch coupling. In this work, we simulate growth...

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Detalles Bibliográficos
Autores principales: Mengel Pers, Benedicte, Krishna, Sandeep, Chakraborty, Sagar, Pigolotti, Simone, Sekara, Vedran, Semsey, Szabolcs, Jensen, Mogens H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492435/
https://www.ncbi.nlm.nih.gov/pubmed/23144963
http://dx.doi.org/10.1371/journal.pone.0048772