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Multi-modal microtubule binding by the Ndc80 kinetochore complex

The Ndc80 complex is a key site of kinetochore-microtubule attachment during cell division. The human complex engages microtubules with a globular “head” formed by tandem calponin-homology domains and an 80 amino-acid unstructured “tail” that contains sites of phospho-regulation by the Aurora B kina...

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Detalles Bibliográficos
Autores principales: Alushin, Gregory M., Musinipally, Vivek, Matson, Daniel, Tooley, John, Stukenberg, P. Todd, Nogales, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492541/
https://www.ncbi.nlm.nih.gov/pubmed/23085714
http://dx.doi.org/10.1038/nsmb.2411