Cargando…
Multi-modal microtubule binding by the Ndc80 kinetochore complex
The Ndc80 complex is a key site of kinetochore-microtubule attachment during cell division. The human complex engages microtubules with a globular “head” formed by tandem calponin-homology domains and an 80 amino-acid unstructured “tail” that contains sites of phospho-regulation by the Aurora B kina...
Autores principales: | Alushin, Gregory M., Musinipally, Vivek, Matson, Daniel, Tooley, John, Stukenberg, P. Todd, Nogales, Eva |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492541/ https://www.ncbi.nlm.nih.gov/pubmed/23085714 http://dx.doi.org/10.1038/nsmb.2411 |
Ejemplares similares
-
The Ndc80 kinetochore complex forms oligomeric arrays along microtubules
por: Alushin, Gregory M., et al.
Publicado: (2010) -
Molecular requirements for the formation of a kinetochore–microtubule interface by Dam1 and Ndc80 complexes
por: Lampert, Fabienne, et al.
Publicado: (2013) -
Stable kinetochore‐microtubule attachment requires loop‐dependent Ndc80‐Ndc80 binding
por: Polley, Soumitra, et al.
Publicado: (2023) -
The Ndc80 complex uses a tripartite attachment point to couple microtubule depolymerization to chromosome movement
por: Tooley, John G., et al.
Publicado: (2011) -
Structure of the Ndc80 complex and its interactions at the yeast kinetochore–microtubule interface
por: Zahm, Jacob A., et al.
Publicado: (2023)