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Systems Biological Approaches Reveal Non-additive Responses and Multiple Crosstalk Mechanisms between TLR and GPCR Signaling

A variety of ligands differ in their capacity to bind the receptor, elicit gene expression, and modulate physiological responses. Such receptors include Toll-like receptors (TLRs), which recognize various patterns of pathogens and lead to primary innate immune activation against invaders, and G-prot...

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Detalles Bibliográficos
Autores principales: Krishnan, Jayalakshmi, Choi, Sangdun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korea Genome Organization 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492651/
https://www.ncbi.nlm.nih.gov/pubmed/23166526
http://dx.doi.org/10.5808/GI.2012.10.3.153