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Systems Biological Approaches Reveal Non-additive Responses and Multiple Crosstalk Mechanisms between TLR and GPCR Signaling
A variety of ligands differ in their capacity to bind the receptor, elicit gene expression, and modulate physiological responses. Such receptors include Toll-like receptors (TLRs), which recognize various patterns of pathogens and lead to primary innate immune activation against invaders, and G-prot...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korea Genome Organization
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492651/ https://www.ncbi.nlm.nih.gov/pubmed/23166526 http://dx.doi.org/10.5808/GI.2012.10.3.153 |