Discovery and Evaluation of Polymorphisms in the AKT2 and AKT3 Promoter Regions for Risk of Korean Lung Cancer

AKT is a signal transduction protein that plays a central role in the tumorigenesis. There are 3 mammalian isoforms of this serine/threonine protein kinase-AKT1, AKT2, and AKT3-showing a broad tissue distribution. We first discovered 2 novel polymorphisms (AKT2 -9826 C/G and AKT3 -811 A/G), and we c...

Descripción completa

Detalles Bibliográficos
Autores principales: Sung, Jae Sook, Park, Kyong Hwa, Kim, Seung Tae, Kim, Yeul Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korea Genome Organization 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492652/
https://www.ncbi.nlm.nih.gov/pubmed/23166527
http://dx.doi.org/10.5808/GI.2012.10.3.167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492652/
https://www.ncbi.nlm.nih.gov/pubmed/23166527
http://dx.doi.org/10.5808/GI.2012.10.3.167

Ejemplares similares