P-Glycoprotein Function at the Blood–Brain Barrier: Effects of Age and Gender

PURPOSE: P-glycoprotein (Pgp) is an efflux transporter involved in transport of several compounds across the blood–brain barrier (BBB). Loss of Pgp function with increasing age may be involved in the development of age-related disorders, but this may differ between males and females. Pgp function ca...

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Detalles Bibliográficos
Autores principales: van Assema, Daniëlle M. E., Lubberink, Mark, Boellaard, Ronald, Schuit, Robert C., Windhorst, Albert D., Scheltens, Philip, Lammertsma, Adriaan A., van Berckel, Bart N. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492696/
https://www.ncbi.nlm.nih.gov/pubmed/22476967
http://dx.doi.org/10.1007/s11307-012-0556-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492696/
https://www.ncbi.nlm.nih.gov/pubmed/22476967
http://dx.doi.org/10.1007/s11307-012-0556-0

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