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DNA Methylation of Tumor Suppressive miRNAs in Non-Hodgkin’s Lymphomas

DNA methylation is an epigenetic alteration leading to heritable phenotypic changes of cells with functional consequences. It is important in early embryonic development, stem cell differentiation, and tissue-specific gene expression. In normal cells, promoter-associated CpG islands (CGI) are genera...

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Detalles Bibliográficos
Autores principales: Yim, Rita Lok-Hay, Kwong, Yok Lam, Wong, Kwan Yeung, Chim, Chor Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492703/
https://www.ncbi.nlm.nih.gov/pubmed/23162567
http://dx.doi.org/10.3389/fgene.2012.00233