Rhein Protects against Obesity and Related Metabolic Disorders through Liver X Receptor-Mediated Uncoupling Protein 1 Upregulation in Brown Adipose Tissue

Liver X receptors (LXRs) play important roles in regulating cholesterol homeostasis, and lipid and energy metabolism. Therefore, LXR ligands could be used for the management of metabolic disorders. We evaluated rhein, a natural compound from Rheum palmatum L., as an antagonist for LXRs and investiga...

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Detalles Bibliográficos
Autores principales: Sheng, Xiaoyan, Zhu, Xuehua, Zhang, Yuebo, Cui, Guoliang, Peng, Linling, Lu, Xiong, Zang, Ying Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2012
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492795/
https://www.ncbi.nlm.nih.gov/pubmed/23139635
http://dx.doi.org/10.7150/ijbs.4575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492795/
https://www.ncbi.nlm.nih.gov/pubmed/23139635
http://dx.doi.org/10.7150/ijbs.4575

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