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TRAF Family Member-Associated NF-κB Activator (TANK) Induced by RANKL Negatively Regulates Osteoclasts Survival and Function

Osteoclasts are the principle bone-resorbing cells. Precise control of balanced osteoclast activity is indispensable for bone homeostasis. Osteoclast activation mediated by RANK-TRAF6 axis has been clearly identified. However, a negative regulation-machinery in osteoclast remains unclear. TRAF famil...

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Detalles Bibliográficos
Autores principales: Wu, Mengrui, Wang, Yiping, Deng, Lianfu, Chen, Wei, Li, Yi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492797/
https://www.ncbi.nlm.nih.gov/pubmed/23139637
http://dx.doi.org/10.7150/ijbs.5079