Cargando…
TRAF Family Member-Associated NF-κB Activator (TANK) Induced by RANKL Negatively Regulates Osteoclasts Survival and Function
Osteoclasts are the principle bone-resorbing cells. Precise control of balanced osteoclast activity is indispensable for bone homeostasis. Osteoclast activation mediated by RANK-TRAF6 axis has been clearly identified. However, a negative regulation-machinery in osteoclast remains unclear. TRAF famil...
Autores principales: | Wu, Mengrui, Wang, Yiping, Deng, Lianfu, Chen, Wei, Li, Yi-Ping |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492797/ https://www.ncbi.nlm.nih.gov/pubmed/23139637 http://dx.doi.org/10.7150/ijbs.5079 |
Ejemplares similares
-
NRROS Negatively Regulates Osteoclast Differentiation by Inhibiting RANKL-Mediated NF-κB and Reactive Oxygen Species Pathways
por: Kim, Jung Ha, et al.
Publicado: (2015) -
TRAF6 neddylation drives inflammatory arthritis by increasing NF-κB activation
por: Liu, Kewei, et al.
Publicado: (2019) -
TRAF6 Autoubiquitination-Independent Activation of the NFκB and MAPK Pathways in Response to IL-1 and RANKL
por: Walsh, Matthew C., et al.
Publicado: (2008) -
The Scaffold Protein TANK/I-TRAF Inhibits NF-κB Activation by Recruiting Polo-like Kinase 1
por: Zhang, Wanqiao, et al.
Publicado: (2010) -
Berberine Sulfate Attenuates Osteoclast Differentiation through RANKL Induced NF-κB and NFAT Pathways
por: Zhou, Lin, et al.
Publicado: (2015)