Preclinical evaluation of racotumomab, an anti-idiotype monoclonal antibody to N-glycolyl-containing gangliosides, with or without chemotherapy in a mouse model of non-small cell lung cancer

N-glycolylneuraminic acid (NeuGc) is a sialic acid molecule usually found in mammalian cells as terminal constituents of different membrane glycoconjugates such as gangliosides. The NeuGcGM3 ganglioside has been described as a tumor antigen for non-small cell lung cancer (NSCLC) in humans. Racotumom...

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Detalles Bibliográficos
Autores principales: Segatori, Valeria I., Vazquez, Ana M., Gomez, Daniel E., Gabri, Mariano R., Alonso, Daniel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492861/
https://www.ncbi.nlm.nih.gov/pubmed/23162791
http://dx.doi.org/10.3389/fonc.2012.00160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492861/
https://www.ncbi.nlm.nih.gov/pubmed/23162791
http://dx.doi.org/10.3389/fonc.2012.00160

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