ROCK/Cdc42-mediated microglial motility and gliapse formation lead to phagocytosis of degenerating dopaminergic neurons in vivo

The role of microglial motility in the context of adult neurodegeneration is poorly understood. In the present work, we investigated the microanatomical details of microglia-neuron interactions in an experimental mouse model of Parkinson's disease following the intraperitoneal injection of MPTP...

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Detalles Bibliográficos
Autores principales: Barcia, Carlos, Ros, Carmen María, Annese, Valentina, Carrillo-de Sauvage, María Angeles, Ros-Bernal, Francisco, Gómez, Aurora, Yuste, José Enrique, Campuzano, Carmen María, de Pablos, Vicente, Fernandez-Villalba, Emiliano, Herrero, María Trinidad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492875/
https://www.ncbi.nlm.nih.gov/pubmed/23139861
http://dx.doi.org/10.1038/srep00809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492875/
https://www.ncbi.nlm.nih.gov/pubmed/23139861
http://dx.doi.org/10.1038/srep00809

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