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Drugs that target pathogen public goods are robust against evolved drug resistance

Pathogen drug resistance is a central problem in medicine and public health. It arises through somatic evolution, by mutation and selection among pathogen cells within a host. Here, we examine the hypothesis that evolution of drug resistance could be reduced by developing drugs that target the secre...

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Detalles Bibliográficos
Autor principal: Pepper, John W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492900/
https://www.ncbi.nlm.nih.gov/pubmed/23144661
http://dx.doi.org/10.1111/j.1752-4571.2012.00254.x