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Permeability of ergot alkaloids across the blood-brain barrier in vitro and influence on the barrier integrity
SCOPE: Ergot alkaloids are secondary metabolites of Claviceps spp. and they have been in the focus of research for many years. Experiments focusing on ergotamine as a former migraine drug referring to the ability to reach the brain revealed controversial results. The question to which extent ergot a...
Autores principales: | Mulac, Dennis, Hüwel, Sabine, Galla, Hans-Joachim, Humpf, Hans-Ulrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492916/ https://www.ncbi.nlm.nih.gov/pubmed/22147614 http://dx.doi.org/10.1002/mnfr.201100431 |
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