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Mitochondria-targeted antioxidant attenuates high glucose-induced P38 MAPK pathway activation in human neuroblastoma cells

Excessive mitochondrial free radical production and the related mitogen-activated protein kinase P38 (P38 MAPK) activation are key regulators in the pathogenesis of high glucose-induced cell stress. Increasing evidence has emphasized the impact of hyperglycemia on neurons and the consequent neuronal...

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Detalles Bibliográficos
Autores principales: CAO, MINGFENG, JIANG, JINJIAO, DU, YIFENG, YAN, PENG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493100/
https://www.ncbi.nlm.nih.gov/pubmed/22245807
http://dx.doi.org/10.3892/mmr.2012.746