Silencing of the polyamine catabolic key enzyme SSAT prevents CDK inhibitor-induced apoptosis in Caco-2 colon cancer cells

Roscovitine and purvalanol are purine derivative cyclin-dependent kinase (CDK) inhibitors that induce apoptosis in various types of cancer cells. However, their impact on the apoptotic cell death mechanism requires further elucidation. Natural polyamines putrescine, spermidine and spermine play esse...

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Detalles Bibliográficos
Autores principales: ÇOKER, A., ARISAN, E.D., PALAVAN-ÜNSAL, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493106/
https://www.ncbi.nlm.nih.gov/pubmed/22294330
http://dx.doi.org/10.3892/mmr.2012.768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493106/
https://www.ncbi.nlm.nih.gov/pubmed/22294330
http://dx.doi.org/10.3892/mmr.2012.768

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