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Lentiviral expression of anti-microRNAs targeting miR-27a inhibits proliferation and invasiveness of U87 glioma cells

Glioma is a highly fatal malignant disease and its treatment options are limited. microRNAs represent a novel target for the treatment of cancer. In the present study, we used a lentiviral vector to stably express anti-microRNAs targeting the oncogenic miR-27a in U87 glioma cells. The stable express...

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Detalles Bibliográficos
Autores principales: FENG, SU Y., DONG, CHANG G., WU, WILLIAM K.K., WANG, XIAO J., QIAO, JIAN, SHAO, JUN F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493108/
https://www.ncbi.nlm.nih.gov/pubmed/22614734
http://dx.doi.org/10.3892/mmr.2012.915