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Knock-down of NDRG2 sensitizes cervical cancer Hela cells to cisplatin through suppressing Bcl-2 expression

BACKGROUND: NDRG2, a member of N-Myc downstream regulated gene family, plays some roles in cellular stress, cell differentiation and tumor suppression. We have found that NDRG2 expression in cervical cancer Hela cells increases significantly upon stimulation with cisplatin, the most popular chemothe...

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Detalles Bibliográficos
Autores principales: Liu, Junye, Yang, Le, Zhang, Jian, Zhang, Jing, Chen, Yongbin, Li, Kangchu, Li, Yurong, Li, Yan, Yao, Libo, Guo, Guozhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493279/
https://www.ncbi.nlm.nih.gov/pubmed/22920753
http://dx.doi.org/10.1186/1471-2407-12-370