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siRNA knockdown of GPR18 receptors in BV-2 microglia attenuates N-arachidonoyl glycine-induced cell migration
BACKGROUND: Neurons are known to employ the endogenous cannabinoid system to communicate with other cells of the CNS. Endocannabioid signaling recruits microglia toward neurons by engaging cannabinoid CB(2) and abnormal cannabidiol (Abn-CBD) receptors. The Abn-CBD receptor is a prominent atypical ca...
Autores principales: | McHugh, Douglas, Wager-Miller, James, Page, Jeremy, Bradshaw, Heather B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493281/ https://www.ncbi.nlm.nih.gov/pubmed/22834922 http://dx.doi.org/10.1186/1750-2187-7-10 |
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