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Astragalus saponins downregulate vascular endothelial growth factor under cobalt chloride-stimulated hypoxia in colon cancer cells

BACKGROUND: Our ongoing research has revealed that total saponins extracted from the medicinal herb Radix Astragali (AST) exhibits significant growth-inhibitory and proapoptotic effects in human cancer cells. In the present study, the potential of AST in controlling angiogenesis was further investig...

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Detalles Bibliográficos
Autores principales: Law, Pui-Ching, Auyeung, Kathy K, Chan, Lok-Yi, Ko, Joshua K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493357/
https://www.ncbi.nlm.nih.gov/pubmed/22992293
http://dx.doi.org/10.1186/1472-6882-12-160