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Stage Progression and Neurological Symptoms in Trypanosoma brucei rhodesiense Sleeping Sickness: Role of the CNS Inflammatory Response

BACKGROUND: Human African trypanosomiasis progresses from an early (hemolymphatic) stage, through CNS invasion to the late (meningoencephalitic) stage. In experimental infections disease progression is associated with neuroinflammatory responses and neurological symptoms, but this concept requires e...

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Detalles Bibliográficos
Autores principales: MacLean, Lorna, Reiber, Hansotto, Kennedy, Peter G. E., Sternberg, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493381/
https://www.ncbi.nlm.nih.gov/pubmed/23145191
http://dx.doi.org/10.1371/journal.pntd.0001857