A novel 7-bromoindirubin with potent anticancer activity suppresses survival of human melanoma cells associated with inhibition of STAT3 and Akt signaling

STAT3 and Akt signaling have been validated as potential molecular targets for treatment of cancers including melanoma. These small molecule inhibitors of STAT3 or Akt signaling are promising for developing anti-melanoma therapeutic agents. MLS-2438, a novel 7-bromoindirubin, a derivative of the nat...

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Detalles Bibliográficos
Autores principales: Liu, Lucy, Kritsanida, Marina, Magiatis, Prokopios, Gaboriaud, Nicolas, Wang, Yan, Wu, Jun, Buettner, Ralf, Yang, Fan, Nam, Sangkil, Skaltsounis, Leandros, Jove, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493432/
https://www.ncbi.nlm.nih.gov/pubmed/22895078
http://dx.doi.org/10.4161/cbt.21781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493432/
https://www.ncbi.nlm.nih.gov/pubmed/22895078
http://dx.doi.org/10.4161/cbt.21781

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