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Evolutionarily Ancient Association of the FoxJ1 Transcription Factor with the Motile Ciliogenic Program
It is generally believed that the last eukaryotic common ancestor (LECA) was a unicellular organism with motile cilia. In the vertebrates, the winged-helix transcription factor FoxJ1 functions as the master regulator of motile cilia biogenesis. Despite the antiquity of cilia, their highly conserved...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493443/ https://www.ncbi.nlm.nih.gov/pubmed/23144623 http://dx.doi.org/10.1371/journal.pgen.1003019 |