Microhomology Directs Diverse DNA Break Repair Pathways and Chromosomal Translocations

Chromosomal structural change triggers carcinogenesis and the formation of other genetic diseases. The breakpoint junctions of these rearrangements often contain small overlapping sequences called “microhomology,” yet the genetic pathway(s) responsible have yet to be defined. We report a simple gene...

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Detalles Bibliográficos
Autores principales: Villarreal, Diana D., Lee, Kihoon, Deem, Angela, Shim, Eun Yong, Malkova, Anna, Lee, Sang Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493447/
https://www.ncbi.nlm.nih.gov/pubmed/23144625
http://dx.doi.org/10.1371/journal.pgen.1003026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493447/
https://www.ncbi.nlm.nih.gov/pubmed/23144625
http://dx.doi.org/10.1371/journal.pgen.1003026

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