Notch-Mediated Suppression of TSC2 Expression Regulates Cell Differentiation in the Drosophila Intestinal Stem Cell Lineage

Epithelial homeostasis in the posterior midgut of Drosophila is maintained by multipotent intestinal stem cells (ISCs). ISCs self-renew and produce enteroblasts (EBs) that differentiate into either enterocytes (ECs) or enteroendocrine cells (EEs) in response to differential Notch (N) activation. Var...

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Detalles Bibliográficos
Autores principales: Kapuria, Subir, Karpac, Jason, Biteau, Benoit, Hwangbo, DaeSung, Jasper, Heinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493453/
https://www.ncbi.nlm.nih.gov/pubmed/23144631
http://dx.doi.org/10.1371/journal.pgen.1003045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493453/
https://www.ncbi.nlm.nih.gov/pubmed/23144631
http://dx.doi.org/10.1371/journal.pgen.1003045

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