Stochastic Modeling of Expression Kinetics Identifies Messenger Half-Lives and Reveals Sequential Waves of Co-ordinated Transcription and Decay

The transcriptome in a cell is finely regulated by a large number of molecular mechanisms able to control the balance between mRNA production and degradation. Recent experimental findings have evidenced that fine and specific regulation of degradation is needed for proper orchestration of a global c...

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Detalles Bibliográficos
Autores principales: Cacace, Filippo, Paci, Paola, Cusimano, Valerio, Germani, Alfredo, Farina, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493476/
https://www.ncbi.nlm.nih.gov/pubmed/23144606
http://dx.doi.org/10.1371/journal.pcbi.1002772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493476/
https://www.ncbi.nlm.nih.gov/pubmed/23144606
http://dx.doi.org/10.1371/journal.pcbi.1002772

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