Changes in JC Virus-Specific T Cell Responses during Natalizumab Treatment and in Natalizumab-Associated Progressive Multifocal Leukoencephalopathy

Progressive multifocal leukoencephalopathy (PML) induced by JC virus (JCV) is a risk for natalizumab-treated multiple sclerosis (MS) patients. Here we characterize the JCV-specific T cell responses in healthy donors and natalizumab-treated MS patients to reveal functional differences that may accoun...

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Detalles Bibliográficos
Autores principales: Perkins, Molly R., Ryschkewitsch, Caroline, Liebner, Julia C., Monaco, Maria Chiara G., Himelfarb, Danielle, Ireland, Sara, Roque, Annelys, Edward, Heather L., Jensen, Peter N., Remington, Gina, Abraham, Thomas, Abraham, Jaspreet, Greenberg, Benjamin, Kaufman, Charles, LaGanke, Chris, Monson, Nancy L., Xu, Xiaoning, Frohman, Elliot, Major, Eugene O., Douek, Daniel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493478/
https://www.ncbi.nlm.nih.gov/pubmed/23144619
http://dx.doi.org/10.1371/journal.ppat.1003014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493478/
https://www.ncbi.nlm.nih.gov/pubmed/23144619
http://dx.doi.org/10.1371/journal.ppat.1003014

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