Variation in the Mechanical Unfolding Pathway of p53DBD Induced by Interaction with p53 N-Terminal Region or DNA

The tumor suppressor p53 plays a crucial role in the cell cycle checkpoints, DNA repair, and apoptosis. p53 consists of a natively unfolded N-terminal region (NTR), central DNA binding domain (DBD), C-terminal tetramerization domain, and regulatory region. In this paper, the interactions between the...

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Detalles Bibliográficos
Autores principales: Taniguchi, Yukinori, Kawakami, Masaru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493487/
https://www.ncbi.nlm.nih.gov/pubmed/23145047
http://dx.doi.org/10.1371/journal.pone.0049003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493487/
https://www.ncbi.nlm.nih.gov/pubmed/23145047
http://dx.doi.org/10.1371/journal.pone.0049003

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