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Imbalances between Matrix Metalloproteinases (MMPs) and Tissue Inhibitor of Metalloproteinases (TIMPs) in Maternal Serum during Preterm Labor

BACKGROUND: Matrix metalloproteinases (MMPs) are involved in remodeling of the extracellular matrix (ECM) during pregnancy and parturition. Aberrant ECM degradation by MMPs or an imbalance between MMPs and their tissue inhibitors (TIMPs) have been implicated in the pathogenesis of preterm labor, how...

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Detalles Bibliográficos
Autores principales: Tency, Inge, Verstraelen, Hans, Kroes, Ivo, Holtappels, Gabriële, Verhasselt, Bruno, Vaneechoutte, Mario, Verhelst, Rita, Temmerman, Marleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493509/
https://www.ncbi.nlm.nih.gov/pubmed/23145060
http://dx.doi.org/10.1371/journal.pone.0049042