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Effects of the CK2 Inhibitors CX-4945 and CX-5011 on Drug-Resistant Cells
CK2 is a pleiotropic protein kinase, which regulates many survival pathways and plays a global anti-apoptotic function. It is highly expressed in tumor cells, and is presently considered a promising therapeutic target. Among the many inhibitors available for this kinase, the recently developed CX-49...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493520/ https://www.ncbi.nlm.nih.gov/pubmed/23145120 http://dx.doi.org/10.1371/journal.pone.0049193 |