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Modeling Amyloid-Beta as Homogeneous Dodecamers and in Complex with Cellular Prion Protein
Soluble amyloid beta (Aβ) peptide has been linked to the pathology of Alzheimer’s disease. A variety of soluble oligomers have been observed to be toxic, ranging from dimers to protofibrils. No tertiary structure has been identified as a single biologically relevant form, though many models are comp...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493521/ https://www.ncbi.nlm.nih.gov/pubmed/23145167 http://dx.doi.org/10.1371/journal.pone.0049375 |