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Paradoxical Relationship between Mn Superoxide Dismutase Deficiency and Radiation-Induced Cognitive Defects

Radiation therapy of the CNS, even at low doses, can lead to deficits in neurocognitive functions. Reduction in hippocampal neurogenesis is usually, but not always, associated with cognitive deficits resulting from radiation therapy. Generation of reactive oxygen species is considered the main cause...

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Detalles Bibliográficos
Autores principales: Corniola, Rikki, Zou, Yani, Leu, David, Fike, John R., Huang, Ting-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493523/
https://www.ncbi.nlm.nih.gov/pubmed/23145165
http://dx.doi.org/10.1371/journal.pone.0049367