Negative Regulation of Hepatitis C Virus Specific Immunity Is Highly Heterogeneous and Modulated by Pegylated Interferon-Alpha/Ribavirin Therapy

Specific inhibitory mechanisms suppress the T-cell response against the hepatitis C virus (HCV) in chronically infected patients. However, the relative importance of suppression by IL-10, TGF-β and regulatory T-cells and the impact of pegylated interferon-alpha and ribavirin (PegIFN-α/ribavirin) the...

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Detalles Bibliográficos
Autores principales: Claassen, Mark A. A., de Knegt, Robert J., Turgut, Duygu, Groothuismink, Zwier M. A., Janssen, Harry L. A., Boonstra, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493527/
https://www.ncbi.nlm.nih.gov/pubmed/23145169
http://dx.doi.org/10.1371/journal.pone.0049389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493527/
https://www.ncbi.nlm.nih.gov/pubmed/23145169
http://dx.doi.org/10.1371/journal.pone.0049389

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