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siRNA Has Greatly Elevated Mismatch Tolerance at 3′-UTR Sites
It has been noted that target sites located in the coding region or the 3′-untranslated region (3′-UTR) can be silenced to significantly different levels by the same siRNA, but little is known about at what specificity the silencing was achieved. In an exploration of positional effects on siRNA spec...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493533/ https://www.ncbi.nlm.nih.gov/pubmed/23145149 http://dx.doi.org/10.1371/journal.pone.0049309 |