The PDZ Protein GIPC Regulates Trafficking of the LPA(1) Receptor from APPL Signaling Endosomes and Attenuates the Cell’s Response to LPA

Lysophosphatidic acid (LPA) mediates diverse cellular responses through the activation of at least six LPA receptors – LPA(1–6,) but the interacting proteins and signaling pathways that mediate the specificity of these receptors are largely unknown. We noticed that LPA(1) contains a PDZ binding moti...

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Detalles Bibliográficos
Autores principales: Varsano, Tal, Taupin, Vanessa, Guo, Lixia, Baterina, Oscar Y., Farquhar, Marilyn G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493537/
https://www.ncbi.nlm.nih.gov/pubmed/23145131
http://dx.doi.org/10.1371/journal.pone.0049227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493537/
https://www.ncbi.nlm.nih.gov/pubmed/23145131
http://dx.doi.org/10.1371/journal.pone.0049227

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