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On the Mechanism of Synaptic Depression Induced by CaMKIIN, an Endogenous Inhibitor of CaMKII

Activity-dependent synaptic plasticity underlies, at least in part, learning and memory processes. NMDA receptor (NMDAR)-dependent long-term potentiation (LTP) is a major synaptic plasticity model. During LTP induction, Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is activated, autophospho...

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Detalles Bibliográficos
Autores principales: Gouet, Camilo, Aburto, Belen, Vergara, Cecilia, Sanhueza, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493544/
https://www.ncbi.nlm.nih.gov/pubmed/23145145
http://dx.doi.org/10.1371/journal.pone.0049293