Role of PheE15 Gate in Ligand Entry and Nitric Oxide Detoxification Function of Mycobacterium tuberculosis Truncated Hemoglobin N

The truncated hemoglobin N, HbN, of Mycobacterium tuberculosis is endowed with a potent nitric oxide dioxygenase (NOD) activity that allows it to relieve nitrosative stress and enhance in vivo survival of its host. Despite its small size, the protein matrix of HbN hosts a two-branched tunnel, consis...

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Detalles Bibliográficos
Autores principales: Oliveira, Ana, Singh, Sandeep, Bidon-Chanal, Axel, Forti, Flavio, Martí, Marcelo A., Boechi, Leonardo, Estrin, Dario A., Dikshit, Kanak L., Luque, F. Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493545/
https://www.ncbi.nlm.nih.gov/pubmed/23145144
http://dx.doi.org/10.1371/journal.pone.0049291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493545/
https://www.ncbi.nlm.nih.gov/pubmed/23145144
http://dx.doi.org/10.1371/journal.pone.0049291

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