Tubulointerstitial De Novo Expression of the α8 Integrin Chain in a Rodent Model of Renal Fibrosis – A Potential Target for Anti-Fibrotic Therapy?

In the normal kidney, the α8 integrin chain is expressed only on mesangial cells and vascular smooth muscle cells. α8 integrin ligates several matrix molecules including fibronectin, osteopontin and fibrillin-1. Recently, we detected de novo expression of α8 integrin on epithelial cells in renal cys...

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Detalles Bibliográficos
Autores principales: Hartner, Andrea, Menendez-Castro, Carlos, Cordasic, Nada, Marek, Ines, Volkert, Gudrun, Klanke, Bernd, Rascher, Wolfgang, Hilgers, Karl F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493553/
https://www.ncbi.nlm.nih.gov/pubmed/23144868
http://dx.doi.org/10.1371/journal.pone.0048362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493553/
https://www.ncbi.nlm.nih.gov/pubmed/23144868
http://dx.doi.org/10.1371/journal.pone.0048362

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