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A Systematic Screen Reveals MicroRNA Clusters That Significantly Regulate Four Major Signaling Pathways

MicroRNAs (miRNAs) are encoded in the genome as individual miRNA genes or as gene clusters transcribed as polycistronic units. About 50% of all miRNAs are estimated to be co-expressed with neighboring miRNAs. Recent studies have begun to illuminate the importance of the clustering of miRNAs from an...

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Detalles Bibliográficos
Autores principales: Becker, Lindsey E., Lu, Zhongxin, Chen, Weiqun, Xiong, Wei, Kong, Maiying, Li, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493556/
https://www.ncbi.nlm.nih.gov/pubmed/23144891
http://dx.doi.org/10.1371/journal.pone.0048474