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Trigeminal Ganglion Neurons of Mice Show Intracellular Chloride Accumulation and Chloride-Dependent Amplification of Capsaicin-Induced Responses
Intracellular Cl(−) concentrations ([Cl(−)](i)) of sensory neurons regulate signal transmission and signal amplification. In dorsal root ganglion (DRG) and olfactory sensory neurons (OSNs), Cl(−) is accumulated by the Na(+)-K(+)-2Cl(−) cotransporter 1 (NKCC1), resulting in a [Cl(−)](i) above electro...
Autores principales: | Schöbel, Nicole, Radtke, Debbie, Lübbert, Matthias, Gisselmann, Günter, Lehmann, Ramona, Cichy, Annika, Schreiner, Benjamin S. P., Altmüller, Janine, Spector, Alan C., Spehr, Jennifer, Hatt, Hanns, Wetzel, Christian H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493563/ https://www.ncbi.nlm.nih.gov/pubmed/23144843 http://dx.doi.org/10.1371/journal.pone.0048005 |
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