Cargando…

Constitutive ß-Catenin Signaling by the Viral Chemokine Receptor US28

Chronic activation of Wnt/ß-catenin signaling is found in a variety of human malignancies including melanoma, colorectal and hepatocellular carcinomas. Interestingly, expression of the HCMV-encoded chemokine receptor US28 in intestinal epithelial cells promotes intestinal neoplasia in transgenic mic...

Descripción completa

Detalles Bibliográficos
Autores principales: Langemeijer, Ellen V., Slinger, Erik, de Munnik, Sabrina, Schreiber, Andreas, Maussang, David, Vischer, Henry, Verkaar, Folkert, Leurs, Rob, Siderius, Marco, Smit, Martine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493591/
https://www.ncbi.nlm.nih.gov/pubmed/23145028
http://dx.doi.org/10.1371/journal.pone.0048935