Cargando…
Constitutive ß-Catenin Signaling by the Viral Chemokine Receptor US28
Chronic activation of Wnt/ß-catenin signaling is found in a variety of human malignancies including melanoma, colorectal and hepatocellular carcinomas. Interestingly, expression of the HCMV-encoded chemokine receptor US28 in intestinal epithelial cells promotes intestinal neoplasia in transgenic mic...
Autores principales: | Langemeijer, Ellen V., Slinger, Erik, de Munnik, Sabrina, Schreiber, Andreas, Maussang, David, Vischer, Henry, Verkaar, Folkert, Leurs, Rob, Siderius, Marco, Smit, Martine J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493591/ https://www.ncbi.nlm.nih.gov/pubmed/23145028 http://dx.doi.org/10.1371/journal.pone.0048935 |
Ejemplares similares
-
The constitutive activity of the virally encoded chemokine receptor US28 accelerates glioblastoma growth
por: Heukers, Raimond, et al.
Publicado: (2018) -
Modulation of cellular signaling by herpesvirus-encoded G protein-coupled receptors
por: de Munnik, Sabrina M., et al.
Publicado: (2015) -
The Viral G Protein-Coupled Receptor ORF74 Hijacks β-Arrestins for Endocytic Trafficking in Response to Human Chemokines
por: de Munnik, Sabrina M., et al.
Publicado: (2015) -
The sorting protein GASP-1 regulates the constitutive signaling capacity of the virally encoded chemokine receptor US28
por: Tschische, Pia, et al.
Publicado: (2009) -
Construction and Experimental Validation of a Petri Net Model of Wnt/β-Catenin Signaling
por: Jacobsen, Annika, et al.
Publicado: (2016)