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Hypoxia-Inducible Factor Activation Protects the Kidney from Gentamicin-Induced Acute Injury

Gentamicin nephrotoxicity is one of the most common causes of acute kidney injury (AKI). Hypoxia-inducible factor (HIF) is effective in protecting the kidney from ischemic and toxic injury. Increased expression of HIF-1α mRNA has been reported in rats with gentamicin-induced renal injury. We hypothe...

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Detalles Bibliográficos
Autores principales: Ahn, Jeong-myung, You, Sun Jin, Lee, Yun-Mi, Oh, Se-Won, Ahn, Shin-young, Kim, Sejoong, Chin, Ho Jun, Chae, Dong-Wan, Na, Ki Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493596/
https://www.ncbi.nlm.nih.gov/pubmed/23145036
http://dx.doi.org/10.1371/journal.pone.0048952