Cargando…

Identification of Novel HIV 1- Protease Inhibitors: Application of Ligand and Structure Based Pharmacophore Mapping and Virtual Screening

A combined ligand and structure-based drug design approach provides a synergistic advantage over either methods performed individually. Present work bestows a good assembly of ligand and structure-based pharmacophore generation concept. Ligand-oriented study was accomplished by employing the HypoGen...

Descripción completa

Detalles Bibliográficos
Autores principales: Yadav, Divya, Paliwal, Sarvesh, Yadav, Rakesh, Pal, Mahima, Pandey, Anubhuti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493599/
https://www.ncbi.nlm.nih.gov/pubmed/23145032
http://dx.doi.org/10.1371/journal.pone.0048942